Protein NMR Spectroscopist

Description

An exciting opportunity has arisen for a Protein NMR Spectroscopist to join our client; a leading drug discovery organisation focused on developing therapeutic solutions for oncology and CNS disorders.

In this position, you will play a key part in supporting a fragment–based drug discovery (FBDD) platform, using advanced NMR techniques to investigate protein ligand interactions and drive early–stage drug discovery projects.

Key Responsibilities

Develop and optimise protein– and ligand–observed NMR assays Conduct NMR–based fragment screening campaigns Characterise hits and generate data on binding affinity, kinetics, and mechanism of action Prepare isotopically labelled protein samples (expression & purification) Analyse and present data to multidisciplinary project teams

Key experience:

Strong expertise in protein NMR spectroscopy; either from academia or industry experience Experience of troubleshooting & maintaining NMR spectroscopy instruments Solid understanding of protein ligand interactions and biophysics Ability to work independently and communicate effectively within cross–functional teams Fragment–based or structure–based drug discovery experience is desirable Experience with other biophysical techniques such as SPR, ITC, MS is desirable

Ad ID: 5418121268